Angiosarcoma and the CDC: Article from 1974

One of the first published articles connecting Angiosarcoma to Vinyl Chloride was recently republished.  The CDC is recognizing it's 50th anniversary and is periodically republishing  articles on several different subjects.

Reprinted below is a report published February 9, 1974, which described the investigation of a cluster of cases of angiosarcoma of the liver among polyvinyl chloride
workers in Kentucky, followed by a contemporary editorial note.

...

Between September 1967 and December 1973, 4 cases of angiosarcoma of the liver were diagnosed among men employed in the polyvinyl chloride polymerization section of a B.F. Goodrich plant near Louisville, Kentucky. This section of the plant began operations in 1938. It employs about 270 persons and produces polyvinyl chloride as well as a variety of copolymers by polymerization of vinyl chloride monomer. All 4 men had worked continuously in the section for at least 14 years prior to onset of illness (Table 1); all 4 had worked directly in various phases of the polymerization process.

One of the more striking statements in the article was the fact that a mere 25 cases a year of Angiosarcoma happen.  With this fact you might see why having 4 cases all in the same department of the same plant was significant.

We are exploring the connection between angiosarcoma and vinyl chloride.  You can read the full reprint of the CDC Angiosarcoma Article here
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